Some old-time residents remember ' Black Sunday', April 14, 1935, as the day of the worst dust storm in the area's history. The Great Depression and the Dust Bowl of the 1930s had a negative effect on Guymon. By 1932, the town had two cream stations and five grain elevators. The 1920 census recorded 1,507 residents, which grew to 2,181 in 1930. Agriculture became the basis of Guymon's economy. A second newspaper, the Guymon Democrat, was in business.

It also had three banks, three hotels, four doctors, a flour mill, a grain company, and several retail establishments. When Oklahoma became a state in 1907, Guymon claimed 839 residents, and was named county seat of the newly created Texas County. Quinn quickly renamed as the Guymon Herald. One of these was the newspaper, Hardesty Herald, which owner Richard B. Guymon's growth was helped when most of the businesses moved there from the nearby town of Hardesty. The town plat was filed in Beaver County, Oklahoma Territory, in 1904. It was renamed Guymon a month later by postal officials to avoid confusion with the town of Stratford, Texas, which was further down the line. Post Office Department, was situated along the line. A community, first named Sanford by the U.S. The site grew very rapidly after the Chicago, Rock Island and Pacific Railway (Rock Island) built a line from Liberal, Kansas, to Texhoma, Texas, in 1901. 'E.T.' Guymon, president of the Inter-State Land and Town Company, purchased a section of land west of the Beaver River, also known as the North Canadian River. Cowboys at Anchor D ranch in Guymon in 1917. History Removing drifts of soil which block highways near Guymon during the Dustbowl. Guymon was the only town or city in Oklahoma in 20 in which the majority of the population was Hispanic. Cattle feedlots, corporate pork farms, and natural gas production dominate its economy, with wind energy production and transmission recently diversifying landowners' farms.

As of the 2020 census, the city population was 12,965, an increase of 13.3% from 11,442 in 2010, and represents more than half of the population of the county, along with being the largest city in the Oklahoma Panhandle. Guymon ( / ˈ ɡ aɪ m ə n/ GHY-mən) is a city and county seat of Texas County, in the panhandle of Oklahoma, United States.

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